Week 14 saves the best for last, with outstanding rivalry matchups that also offer potentially strong college football odds value.
On Friday night, the Purdue Boilermakers host the Indiana Hoosiers for the Old Oaken Bucket. Kickoff on NBC is at 7:30 p.m. ET.
Another Big Ten rivalry, known as The Game, kicks off on FOX Big Noon Saturday at Noon, ET when the Michigan Wolverines host the Ohio State Buckeyes at the Big House.
In the SEC, the Arkansas Razorbacks host the Missouri Tigers on Saturday at 3:30 p.m. ET with coverage on SECN.
The Kansas State Wildcats will host the Colorado Buffaloes at Noon ET in a Big 12 matchup with coverage on FS1.
USC will host UCLA in a Big Ten rivalry showdown that comes from the old Pac-12. Kickoff is at 7:30 p.m. ET with coverage on NBC.
Notable CFB Week 14 Odds
South Carolina (-2.5) is an intriguing price at home against Clemson. Clemson has fallen far short of expectations while underachieving South Carolina can salvage its pride with a win over their rivals. Some gamblers will be intrigued by the power brand of Clemson as the underdog.
Florida State (+3.5) is an interesting line against Florida. Florida State head coach Mike Norvell needs a win to change the negative narrative and salvage a bowl bid. Florida is wrapping up a lost season with an interim coach.
Minnesota (-2.5) catches attention in its home finale against Wisconsin in the battle for Paul Bunyan’s axe. Wisconsin has lost its culture, identity, and winning ways with head coach Luke Fickell, who would be fired if the buyout wasn’t so expensive. But the Badgers have won two of their last three since confirming Fickell’s return, while Minnesota lost a heartbreaker at Northwestern last Saturday.
CFB Week 14 Predictions
Indiana -28.5 at Purdue – The Hoosiers are powering toward the College Football Playoff and face a rebuilding Purdue team that is winless in the Big Ten. Indiana fans are certain to take over Ross-Ade Stadium and make it into a Hoosier home game.
Ohio State –11.5 at Michigan – The Buckeyes are desperately trying to turn the tide against their hated arch rival, known as “That Team Up North.” Michigan has won four in a row against the Buckeyes, who won the 2024 national championship after a soul-crushing loss to Michigan. Of course, most Buckeye fans would rather beat the Maize and Blue than win the national title. This year, the Ohio State defense should be the difference and end the misery for the Bucks.
Missouri -1.5 at Arkansas – The Razorbacks are winding up a lost season under interim head coach Bobby Petrino, who may end up as the default head coach anyway. Mizzou has had the advantage in this series and plays hard for head coach Eli Drinkwitz. Arkansas has one of the most putrid defenses in college football.
Kansas State -17.5 vs. Colorado – Coach Prime and the Buffs have a difficult road assignment against a K-State team in need of a win to gain bowl eligibility. It has been a disappointing season for both teams, but the Wildcats are the better group in this Big 12 matchup. This is a must-win game for K-State after a cruel loss at Utah, which will test them mentally. A more talented, desperate team outclasses Colorado.
USC -18.5 vs. UCLA – Despite last week’s loss at Oregon, the Trojans have had a surprisingly good season and face an outclassed UCLA team that has had its moments but has not been able to sustain consistent success.
CFB Week 14 Betting Tips
Indiana covered the spread in only seven of its last 20 games.
Texas A&M covered only five of its last 16 games.
Texas beat Texas A&M straight up in four of their last five meetings.
Clemson is 5-11 against the spread in its last 16 games.
Michigan covered the spread in only two of its most recent seven games.
Colorado covered the spread in only one of its last six games.
Kansas State covered the spread in five of its most recent seven games with Colorado.
Wisconsin got the money in four of its last five games.
Minnesota covered four of its last five games against Wisconsin.
PRIME Week 14 Best Bets: Indiana Hoosiers, Ohio State Buckeyes, Missouri Tigers, USC Trojans, Kansas State Wildcats
