The sports betting weekday builds toward one of the most active stretches of the sports calendar, with March Madness taking center stage as the NCAA Tournament reaches the Sweet Sixteen on Thursday and Friday. After a full week of opening-round action, the remaining teams shift into regional play, with matchups spread across CBS and TBS from early evening into late night.

Earlier in the week, the NIT moves into its quarterfinal round on Tuesday and Wednesday, providing additional postseason college basketball coverage and betting opportunities leading into the weekend.

Beyond college basketball, the sports calendar expands with the start of the Major League Baseball season. The standalone opener on Wednesday night features the New York Yankees and San Francisco Giants on a national stage, before the rest of the teams begin play on Thursday and Friday.

With nationally televised windows across NBC, Peacock, and Apple TV+, baseball returns with immediate impact, adding daytime and primetime options throughout the latter half of the week.

The NBA and NHL continue their regular-season schedules with select nationally televised games each night, while the TGL Finals Series opens the week with a best-of-three championship set on ESPN platforms. Friday also marks the start of UFL Week 1, bringing spring football back into the national spotlight.

With postseason basketball, Opening Day baseball, and multiple leagues active across the week, the weekday schedule offers consistent betting opportunities from afternoon through late night.

Major Events This Week

March 23–24: TGL Finals Series
March 25: MLB Season Opener — New York Yankees at San Francisco Giants
March 26–27: MLB Opening Day for all other teams.
March 26–27: NCAA Men’s Basketball Tournament Sweet Sixteen
March 26–29: Texas Children’s Houston Open
March 27–29: UFL Week 1

MONDAY — March 23

NBA

San Antonio at Miami — 7:00 PM, Peacock/NBCSN
Golden State at Dallas — 9:30 PM, Peacock/NBCSN
(Other games not nationally televised.)

NHL

Ottawa at New York — 7:30 PM, NHL Network

TGL Finals Series

Jupiter vs. Los Angeles
Match 1 — 9:00 PM, ESPN2

TUESDAY — March 24

NBA

Orlando at Cleveland — 8:00 PM, NBC/Peacock
Denver at Phoenix — 11:00 PM, NBC/Peacock
(Other games not nationally televised.)

College Basketball — NIT (Quarterfinals)

Wichita State at Tulsa — 7:00 PM, ESPN2
Saint Joseph’s at New Mexico — 9:00 PM, ESPN2

NHL

Minnesota at Tampa Bay — 7:30 PM, TNT / truTV / HBO Max
(All other games are ESPN+ only.)

TGL Finals Series

Jupiter vs. Los Angeles
Match 2 — 7:00 PM, ESPN
Match 3 (if necessary) — 9:00 PM, ESPN

WEDNESDAY — March 25

NBA

Atlanta at Detroit — 7:00 PM, ESPN
Houston at Minnesota — 9:30 PM, ESPN
(Other games not nationally televised.)

College Basketball — NIT (Quarterfinals)

Illinois State at Dayton — 7:00 PM, ESPN2
Nevada at Auburn — 9:00 PM, ESPN2

MLB — Season Opener

New York Yankees at San Francisco — 8:05 PM, Netflix

NHL

Boston at Buffalo — 7:30 PM, TNT / truTV / HBO Max
(All other games are ESPN+ only.)

THURSDAY — March 26

NBA

New York at Charlotte — 7:00 PM, NBA TV
(Other games not nationally televised.)

College Basketball — NCAA Tournament (Sweet Sixteen)

(11) Texas vs. (2) Purdue — 7:10 PM, CBS
(9) Iowa vs. (4) Nebraska — 7:30 PM, TBS / truTV
(4) Arkansas vs. (1) Arizona — 9:45 PM, CBS
(3) Illinois vs. (2) Houston — 10:05 PM, TBS / truTV

MLB — Opening Day

Pittsburgh at New York Mets — 1:15 PM, NBC/Peacock
Arizona at Los Angeles Dodgers — 8:30 PM, NBC/Peacock
(All other games are MLB.TV only.)

NHL

Minnesota at Florida — 7:00 PM, ESPN
Edmonton at Vegas — 9:30 PM, ESPN
(All other games are ESPN+ only.)

Golf

Texas Children’s Houston Open — First Round, Golf Channel

FRIDAY — March 27

NBA

Miami at Cleveland — 7:30 PM, NBA TV
Chicago at Oklahoma City — 8:00 PM, NBA TV
Dallas at Portland — 10:00 PM, NBA TV
(Other games not nationally televised.)

College Basketball — NCAA Tournament (Sweet Sixteen)

(5) St. John’s vs. (1) Duke — 7:10 PM, CBS
(4) Alabama vs. (1) Michigan — 7:35 PM, TBS / truTV
(3) Michigan State vs. (2) UConn — 9:45 PM, CBS
(6) Tennessee vs. (2) Iowa State — 10:10 PM, TBS / truTV