NHL: Red Wings at Sabres Betting Preview

On Wednesday night, TNT will bring fans and gamblers an intriguing matchup of two teams that have long been out of the playoff picture but are striving to get back in.

The Detroit Red Wings last made the playoffs in 2016 and have been rebuilding ever since. Detroit fans are growing impatient and demanding a playoff spot this year.

Since 2011, the Buffalo Sabers have not been in the NHL betting odds postseason. Fans continue to hope that the misery will end this year.  Buffalo and Detroit need every win that they can get.

The Red Wings' hot start has caught the attention of gamblers who are starting to believe that this could finally be the year for Detroit to get back into the 2025 Stanley Cup Playoffs.

Red Wings at Sabres Preview

On Wednesday, October 22, 2025, the Buffalo Sabres will host the Detroit Red Wings at KeyBank Center in Buffalo, NY. Faceoff time is 7:30 p.m. ET with television coverage on TNT.

Public Betting Odds Factors

• The Detroit Red Wings are one of the most popular teams on the board.

• As an Original Six team that was once a regular playoff participant, the Detroit brand still has a sports betting cachet.

• On the other hand, the Buffalo Sabres have been so bad for so long that gamblers avoid them.

• In fact, the Sabres only draw NHL betting activity in opposition to them. Buffalo has been a regular bankroll buster for the past decade.

Red Wings at Sabres Predictions

Handicapping Factors to Consider 

• In this situation, we have two teams already under pressure.

• Detroit has come closer than Buffalo to making the playoffs the past two years.

• In the early portion of this season, Detroit looks closer to making the Stanley Cup Playoffs.

• Detroit is getting the more favorable road team price against a wildly inconsistent Buffalo team.

• To conclude, Detroit makes the most sense with the road club discount.

Red Wings at Sabres Prime Best Bet: Detroit Red Wings 

Red Wings at Sabres Betting Tips

Detroit Red Wings 

• At the onset of the season, the Detroit Red Wings won four consecutive games after dropping the season opener. Only one of those games went over the total.

• The Red Wings took the lead in the Atlantic Division standings.

• Overall, Detroit ranks 11^th for goal scoring, 5^th for power play efficiency, 9^th for goals against, and 9^th for penalty killing.

• First among Detroit scorers is C Dylan Larkin with three goals, four assists, seven points, and a +7.

• RW Alex DeBrincat added six assists.

• Veteran RW Patrick Kane has two goals, three assists, and five points.

• G Cam Talbot has three starts with a 3-0 record and a 1.78 goals against average, and a .932 save percentage.

• G John Gibson has two starts with a record of 1-1 and a 3.57 goals against average and a .867 save percentage.

Buffalo Sabres 

• Following a 0-3 start, the Buffalo Sabres won their next two games. Four of the five games went under the total.

• Buffalo ranks 28^th for goal scoring, 5^th for power play efficiency, 13^th for fewest goals against, and 1^st for penalty killing.

• So far, RW Josh Doan is making a good impression with his new team.

•  Doan arrived from the Utah Mammoth and leads Buffalo with two goals, three assists, and a +1.

• LW Jason Tucker adds three goals and an assist.

• G Alex Lyon played in all five games and posted an impressive 2.43 goals against average and a .929 save percentage.

Red Wings at Sabres Head-to-Head and Key Stats

• Four of the Red Wings last seven road games went under the total.

• Buffalo has been a good home ice NHL betting odds value with 14 payouts in its most recent 19 games at KeyBank Center.

• Five of their last seven home games went under the total.

• In the series between Buffalo and Detroit, the Red Wings got the money in six of the most recent eight meetings.

• Nine of the last 12 games between the Red Wings and Sabres in Buffalo went over the total.