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NBA Betting Tips: 76ers at Knicks

Once upon a time, the Philadelphia 76ers were totally dependent upon the health of Joel Embiid for their success.

However, head coach Nick Nurse has created a way for the Sixers to power through without the frequently injured Embiid.

Tyrese Maxey has become the marquee man of the 76ers. Maxey has emerged as a key asset, averaging 31.1 points and 7.1 assists per game.

On Friday night, the Sixers have a tough road assignment against the New York Knicks.

New York is continuing to build on its success from last year. Jalen Brunson mans the New York marquee with over 28 points per game.

Most importantly, head coach Mike Brown has not compromised the quality standards set by his predecessor, Tom Thibodeau.

The Sixers and Knicks are two of the NBA’s legacy franchises with large followings. Thus, there will be plenty of NBA betting interest for this Amazon Prime Friday night feature.

76ers at Knicks Preview

On Friday, December 19, 2025, the New York Knicks will host the Philadelphia 76ers at Madison Square Garden, New York. Tipoff is 7 p.m. ET, with television coverage on Amazon Prime Video.

Public Betting Odds Factors

  • Bargain hunters and sharps will consider the value of the 76ers. Philadelphia is a quality club getting the enhanced road team price.
  • Wise Guys are concerned that the casual sector will bet the Knicks up into an overlay as the power home team.

76ers at Knicks Predictions

Handicapping Factors to Consider 

  • In this situation, Philadelphia will offer more value with the road team price.
  • As mentioned above, the 76ers have shown proven profitability in New York.
  • The Knicks will be overpriced at home based on branding and record.
  • New York’s NBA Cup triumph only adds to its price tag.

76ers at Knicks Prime Best Bet: Philadelphia 76ers and Under the Total

76ers at Knicks Betting Tips

Philadelphia 76ers 

  • The Philadelphia 76ers are 14-11 straight up, 15-9-1 against the NBA odds, and 12-13 over/under the total.
  • Philadelphia has covered three out of their last four games. At the same time, the 76ers have gone under the total in five of their previous six matchups.
  • Philadelphia is 6th in the Eastern Conference playoff standings.  Philadelphia is 6.5 games behind the Detroit Pistons in the Eastern Conference playoff race.
  • Philadelphia ranks 16th in scoring offense, 26th in field goal percentage, 14th in 3-point field goal percentage, 6th in free throw percentage, and 7th in offensive rebounding.
  • On defense, the 76ers rank 12th in scoring defense, 8th in field goal percentage allowed, 8th in 3-point field goal percentage allowed, and 21st in defensive rebounding.

New York Knicks 

  • The New York Knicks are 18-7 straight up, 17-8 against the spread, and 13-12 over/under the total.
  • New York has covered 10 out of their last 11 games. At the same time, the Knicks have gone over the total in three of their previous five matchups.
  • New York is 2nd in the Eastern Conference playoff standings.  New York is 2.5 games behind the Detroit Pistons in the Eastern Conference playoff race.
  • New York ranks 4th in scoring offense, 11th in field goal percentage, 5th in 3-point field goal percentage, 11th in free throw percentage, and 5th in offensive rebounding.
  • On defense, the Knicks rank 4th in scoring defense, 5th in field goal percentage allowed, 16th in 3-point field goal percentage allowed, and 5th in defensive rebounding.

76ers at Knicks Head-to-Head and Key Stats

  • New York covered the spread in four of their most recent five games with Philadelphia.
  • Three of the last four games between the Knicks and 76ers went under the total.
  • The 76ers covered the spread in three of their last four away games against the Knicks.
  • The 76ers and Knicks went under the total in six of their most recent eight games at Madison Square Garden.
  • Philadelphia covered the spread in nine of its most recent 11 away games.
  • Philadelphia went under the total in four of its most recent six road tilts.
  • The Knicks covered the spread in 16 of their last 19 games at Madison Square Garden.
  • The Knicks went under the total in four of their last five home games.

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