Michigan at Nebraska Game Odds, Predictions & Best Bets

The Nebraska Cornhuskers put their perfect 3-0 record on the line Saturday when they host the Michigan Wolverines in the Big Ten opener for both squads. The competition definitely ramps up for the Huskers after beating Akron and Houston Christian by a combined score of 127-7 the last two weeks. The game is scheduled to kickoff at 3:30 p.m. ET from Memorial Stadium in Lincoln, NE on Saturday, September 20. CBS will provide television coverage. Michigan is listed as a slight favorite in college football odds.

Michigan at Nebraska Preview

Michigan rebounded from a loss at Oklahoma in Week 2 by trouncing Central Michigan 63-3 last Saturday. It was a perfect response for a team that lost a tough one on the road to a ranked foe and had struggled to put away Group of 5 opponents in the past. UM earned its first payout on the college football betting line in the last six tries against a G5 program and covered for the first time this season.

The dual threat ability of Bryce Underwood is the perfect weapon for Nebraska’s aggressive, swarming defense. Underwood showed off against CMU rushing for 114 yards and two TDs on nine carries and throwing for 235 yards with another score. The Wolverines amassed 625 total yards, converted 8 of 11 third downs and possessed the football for more than 33 minutes.

Michigan averages nearly 243 rushing yards per game and has 12 rushing TDs.
Justice Haynes leads the Big Ten with 388 rushing yards averaging 8.0 yards per carry.
UM is 10-1 SU and 8-3 ATS in its last 11 games as a road favorite.
The defense allowed 20 points or less in six of the last seven games overall.

Coach Matt Rhule has a history of turning programs around and he’s had a nice start in 2025. Last season Nebraska had a winning record for the first time in eight years and they’ve yet to lose this season. It’s one thing beating an Akron squad that’s gone 11-58 since the 2019 season and an overmatched FCS squad, but beating a ranked team will go a long way.

A year of seasoning has helped blue chip recruit Dylan Raiola and his development. Playing against weak defenses has also helped, but Raiola is off to a sizzling start completing 76.6 percent of his passes for 829 yards with eight TDs and zero interceptions. The Huskers have the fifth-best passing attack in the country and average 49 points a game.

Nebraska is 13-31 against Big Ten opponents over the last 5 seasons.
The Huskers have lost 27 straight games to ranked opponents going 10-15-2 ATS in those games.
The defense has allowed an average of just 8.0 points and has held its last five opponents to 17 points or less.
Raiola is second in the Big Ten in completion percentage and TD passes.

Michigan at Nebraska Predictions

Having Nebraska relevant again is good for college football, but I’m not convinced they’re back looking at their schedule. They haven’t faced a defense like Michigan’s and 2.5-points is an easy number for the Wolverines to cover. UM will also lock down on Raiola making the UNDER on his passing yard total of 272.5 a good bet.

Michigan at Nebraska Betting Tips

Michigan opened as a 2.5-point favorite with a moneyline price of -128.
Nebraska is 1-8 SU and 4-5 ATS in its nine games as a home dog.
The Huskers are +112 on the moneyline.
The Wolverines are 13-5 ATS in their last 18 road games.
The college football betting total surfaced at 46.5.

Michigan at Nebraska Head to Head and Key Stats

Michigan won the most recent meeting, 45-7, in Lincoln in 2023.
The Wolverines have won four straight with four payouts scoring an average of 41.8 points in those games.
The teams have cashed the OVER in three of the last four matchups.
UM won the last two meetings in Nebraska by a combined score of 77-36.
Nebraska has lost 27 straight to ranked foes since beating No. 22 Oregon in 2016.