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Florida State at Virginia Betting Picks & Odds

The horrible nightmare of the 2024 Florida State Seminoles appears to be clearly in the rear-view mirror. Following their ACC title in 2023, Florida State never recovered and completely collapsed in 2024. As a result of that catastrophe, Florida State head coach Mike Norvell made significant changes to his staff and in the transfer portal for this season. At the onset of the season, the Seminoles upset the Alabama Crimson Tide to announce to the country that they are back. This week brings a tricky road game at the Virginia Cavaliers. So far, Virginia appears to be an improved program.

Florida State at Virginia Preview

On Friday, September 26, 2025, the Virginia Cavaliers will host the Florida State Seminoles at Scott Stadium in Charlottesville, VA. Kickoff time is 7 p.m. ET with television coverage on ESPN.

The Florida State Seminoles opened as a 7-point road favorite.

The Virginia Cavaliers are a 7-point home dog in college football odds.

The Seminoles and Cavaliers opened with a total of 57.5.

Florida State is a -245 moneyline favorite.

Virginia is a +200 home dog.

Betting Odds Factors to Consider 

  • Despite their horrible 2024 season, Florida State is a much bigger public brand than Virginia.
  • Florida State is rapidly regaining respect after beating Alabama to start the year
  • Virginia is improved, but gamblers will need to see a lot more to take a risk on them.
  • Because of branding reputations, Florida State may be overpriced, while Virginia will get looks from bargain hunters.

Florida State at Virginia Predictions

Handicapping Factors to Consider 

  • In this situation, Florida State offers more value as a power program with a road team discount.
  • Florida State has a significant roster advantage and more playmakers.
  • The Seminoles will enter the game with more confidence with momentum, and brand cache.
  • There will be plenty of Florida State fans making the trip.

Florida State at Virginia Prime Best Bet: Florida State Seminoles 

Florida State at Virginia Betting Tips

Florida State Seminoles 

  • Overall, Florida State ranks 1st for total offense and scoring. The Noles rank 2nd for rushing offense. By contrast, Florida State ranks 21st for total offense and 12th for fewest points allowed.
  • Last week, the Florida State Seminoles won 66-10 against the Kent State Golden Flashes as 45-point home favorites. The game went over the total of 56.6. As a result, Florida State is 3-0 straight up, against the spread, and over the total.
  • Consider that FSU finished with 775 yards of offense. That marks the second straight week the Seminoles surpassed 700 yards after previously not having done so since 2000. They averaged a gaudy 9.9 yards per play.

Virginia Cavaliers 

  • To summarize, Virginia has national metrics of 5th for total offense and 11th for scoring. The Cavaliers rank 43rd for total defense and 47th for fewest points allowed.
  • Last week, the Virginia Cavaliers won 48-20 against the Stanford Cardinal as 16.5-point home favorites. The game went over the total of 48. Now, Virginia is 3-1 straight up, 3-1 against the spread, and 4-0 over the total.
  • Chandler Morris threw three first-quarter touchdown passes to Trell Harris to spark Virginia’s victory against Stanford Saturday night.
  • Overall, Morris passed for a season-high 380 yards and four TDs, and he ran for a score.
  • Harris finished with four catches for a career-high 145 yards for the Cavaliers in their inaugural meeting with the Cardinal.

Get all the latest NCAA Football odds at primesportsbook.com

Florida State at Virginia Head-to-Head and Key Stats

Florida State has been a reliable road betting value with ten payouts in its last 15 games in that role.

Florida State went under the total in 13 of their most recent 19 away games.

By contrast, Virginia has been in the black at home. The Cavaliers covered the spread in 11 of their most recent 17 home games.

Virginia went under the total in six of their previous eight home games.

In the series between Virginia and Florida State, the Seminoles covered only three of the last nine meetings.

Nine of the last ten games between Virginia and Florida State have gone under the total.

Specifically in Virginia, the Cavaliers covered only two of their most recent six home games against the Seminoles.

Florida State and Virginia went under the college football betting total in five of their last six meetings at Virginia.

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