# NFL Week 7: Vikings at Chargers Betting Preview

> The Chargers host the Vikings on Thursday Night Football as 2.5-point favorites, with Justin Herbert leading LA against Minnesota’s QB uncertainty.

Published 2025-10-20 · Updated 2026-04-22 · By [Rock Westfall](https://www.primesportsbook.com/author/rockwestfall/)

Since being named head coach of the Minnesota Vikings in 2022, Kevin O’Connell has exceeded expectations.

O’Connell arrived with a strong offensive reputation after serving under Los Angeles Rams mastermind Sean McVay.

Certainly, O’Connell has faced a revolving door of quarterbacks since his arrival. Kirk Cousins, Sam Darnold, JJ McCarthy, and Carson Wentz are among the top names who have been a Minnesota QB under O’Connell.

McCarthy opened the season as the starter, but has been injured, and Wentz has been questionable after taking over.

Minnesota has a challenging game against the Los Angeles Chargers on Thursday night, streaming on Prime Video.

After a hot start, the Chargers have begun to fade.

## Vikings at Chargers Preview

On Thursday, October 23, 2025, the Los Angeles Chargers will host the Minnesota Vikings at SoFi Stadium in Inglewood, CA. Kickoff time is 8:15 p.m. ET with television coverage on Prime Video.

## Public Betting Odds Factors

- Gamblers continue to be frustrated over the Vikings’ inconsistency.

- Additionally, Minnesota lacks a stable quarterback situation.

- Offensively, the Vikings do not inspire confidence. Both teams have good defenses in this matchup.

- Thus, some undertakers will be looking to bet the total.

- The Chargers have been bleeding red ink lately

- Gamblers are increasingly annoyed with Jim Harbaugh and LA.

## Vikings at Chargers Predictions

### Handicapping Factors to Consider

- The Minnesota starting quarterback should be checked by gamblers.

- Both QBs Carson Wentz and JJ McCarthy have been in and out of the Minnesota lineup.

- The Chargers are gaining traction with gamblers for being a quality value.

- Los Angeles has one of the toughest defenses in the NFL.

- The Chargers have the more stable lineup and better quarterback with Justin Herbert

- LA has been a reliable bet at home.

**Vikings at Chargers Prime Best Bet:** **Los Angeles Chargers**

## Vikings at Chargers Betting Tips

Los Angeles opened as a 2.5-point favorite and a -144 moneyline chalk.

Minnesota opened as a [2.5-point dog](https://www.primesportsbook.com/sports/football/nfl/) and a +122 moneyline dog.

The Vikings and Rams opened with a total of 43.5.

### Minnesota Vikings

- Minnesota ranks 20th for total offense, 17th for passing, 22nd for rushing, 14th for scoring, and 27th for fewest turnovers committed.

- In comparison, Minnesota ranks 8th for total defense, 7th vs. the pass, 17th vs. rush, 12th for fewest points allowed, and 26th for takeaways.

- Last game, the Minnesota Vikings lost 28-22 against the Philadelphia Eagles as 2.5-point home dogs. The game went over the total of 43.5.

- As a result, Minnesota is 3-3 straight up, 3-3 against the spread, and 5-1 over/under the total.

### Los Angeles Chargers

- Overall, Los Angeles ranks 6th for total offense, 4th for passing, 18th for rushing, 22nd for scoring, and 26th for fewest turnovers committed.

- Los Angeles ranks 12th for total defense, 8th vs. the pass, 19th vs rush, 17th for fewest points allowed, and 9th for takeaways.

- Last game, the Los Angeles Chargers lost 38-24 against the Indianapolis Colts as 2.5-point home favorites. The game went over the total of 49.

- Now, Los Angeles is 4-3 straight up, 2-4-1 [against the spread](https://www.primesportsbook.com/sports/football/nfl/), and 3-4 over/under the total.

## Vikings at Chargers Head-to-Head and Key Stats

- In the series between Minnesota and Los Angeles, the Vikings covered the spread in five of their last six games vs. the Chargers.

- The Vikings and Chargers went under the total in four of their most recent five meetings.

- Specifically at LA, Minnesota covered its last three visits against the Chargers.

- Two of the most recent three games between the Vikings and Chargers in LA went under the total.

- Minnesota has been a good betting value on the road.

- The Vikings lost only five of their last 20 away games to the spread.

- Five of Minnesota’s last six away games went over the total.

- The Chargers have been good betting values at home.

- Los Angeles got the cash in six of their most recent nine home games.

- Six of the last eight home games for the Chargers went over the total.

Source: https://www.primesportsbook.com/gaming-insider/nfl-week-7-vikings-at-chargers-betting-preview/
