# NFL Games Today: Cardinals vs. Giants Odds & Predictions

> Bet Cardinals vs. Giants at Prime Sportsbook. Get NFL odds, lines, stats, predictions, player props and key matchup insights.

Published 2026-09-30 · By [Tom Wilkinson](https://www.primesportsbook.com/author/tom/)

Arizona visits the New York Giants at 1 pm Eastern on CBS in one of the more evenly priced games on the Week 4 schedule. [**Prime Sportsbook**](https://www.primesportsbook.com/sports/football/nfl/) has the Cardinals favored by 1.5 points with a total of 44.5. Arizona is 1-2 after consecutive losses, while New York is 2-1 following a 12-7 win over Tennessee. Both NFL teams are 2-1 against the spread, and the football game offers a contrast between Arizona’s more productive offense and a Giants defense that has been steadier through three weeks.

## **NFL Games Today and Tonight**

Sunday starts in London with Indianapolis against Washington before the afternoon schedule begins. Arizona at New York kicks off at 1 pm Eastern on CBS, alongside New England at Buffalo, Green Bay at Tampa Bay and Jacksonville at Cincinnati. Anyone asking who plays football tonight gets Detroit at Carolina in the Sunday night spot.

### **Who Plays Football Tonight?**

Detroit visits Carolina at 8:20 pm Eastern on NBC. Week 4 finishes Monday when Atlanta plays at New Orleans at 8:15 pm Eastern on ESPN.

### **Top NFL Matchups to Watch Today**

Cardinals-Giants deserves attention because Arizona is favored by only 1.5 points and both teams have covered two of their first three games.

## **NFL Odds for Today’s Games**

Prime Sportsbook has Arizona -1.5 at -109 and New York +1.5 at -107. The Cardinals are -130 on the moneyline, while the Giants are +114. Those [**NFL odds**](https://www.primesportsbook.com/sports/football/nfl/) make this close to a pick’em compared with larger spreads elsewhere on Sunday.

### **NFL Moneyline and Point Spread Odds**

Arizona needs to win by at least two points to cover. New York gets 1.5 points at home, and the +114 moneyline offers a plus-money return for bettors who think the Giants can win outright.

### **NFL Totals and Over/Under Lines**

The total is 44.5. The Over is -105, while the Under is -111. Arizona and New York are both 1-2 to the Over through three games.

## **NFL Matchup Previews**

These NFL teams have reached the same 2-1 ATS record in different ways. Arizona averages 303.0 total yards and 21.0 points per game, while New York averages 271.3 yards and 15.3 points. The Giants have been better defensively, allowing 329.0 total yards per game compared with Arizona’s 362.0.

### **Offense vs. Defense Matchups**

New York’s best offensive opportunity may be on the ground. The Giants average 118.3 rushing yards per game, and Arizona allows 127.7. Arizona averages only 93.0 rushing yards, while New York gives up 104.3.

### **Key Matchup Advantages**

The NFL stats favor New York defensively, while Arizona owns the more productive passing game. That balance should keep the football game competitive.

## **NFL Players to Watch Today**

The NFL players to watch start with Arizona quarterback Jacoby Brissett and Giants running back Cam Skattebo. Brissett has 652 passing yards, while Skattebo leads New York with 177 rushing yards.

### **Quarterbacks and Offensive Playmakers**

Brissett has four touchdown passes and one interception, including two scores against San Francisco last week. Jeremiyah Love leads Arizona with 160 rushing yards, and Trey McBride has 211 receiving yards. Jaxson Dart leads Giants passers with 250 yards, while Isaiah Likely has a team-high 124 receiving yards.

### **Defensive Players Who Could Impact the Game**

Budda Baker has 1.5 sacks for Arizona. New York’s Abdul Carter has 1.0 sack, and Jevon Holland has three interceptions.

## **NFL Stats to Know Before Today’s Games**

The NFL stats help explain why New York can stay competitive despite ranking 29th in total offense at 271.3 yards per game. The Giants defense has allowed 329.0 yards and 18.3 points per game.

### **Offensive and Defensive NFL Stats**

Arizona averages 303.0 total yards, including 210.0 passing and 93.0 rushing. New York averages 153.0 passing yards and 118.3 rushing yards. The Cardinals have allowed 362.0 total yards per game.

### **Recent Team and Player Trends**

Arizona has lost two straight but covered in last week’s 36-30 loss at San Francisco. New York rebounded from a 28-6 loss to the Rams by beating Tennessee 12-7. Brissett threw two touchdowns without an interception last week, while Skattebo remains the Giants’ leading rusher.

## **NFL Lines and Betting Movement**

The [**NFL lines**](https://www.primesportsbook.com/sports/football/nfl/) have been steadier on the side than on the total. Arizona has stayed around a 1.5-point favorite, while the scoring number has climbed.

### **Opening Lines vs. Current NFL Lines**

The total was 42.5 earlier in the week and is now 44.5 at Prime Sportsbook. Arizona remains -1.5 at -109, with New York +1.5 at -107. That two-point increase is the most noticeable movement in the NFL odds.

### **What Can Move NFL Odds Before Kickoff?**

Player availability, weather or heavier action on one side can still affect the number. With the spread at only 1.5 points, even a small move could change how bettors approach the game.

## **NFL Predictions for Today’s Games**

New York’s defense gives the Giants a path to control a football game in which neither side owns a large advantage. Arizona has produced more offense, but the Cardinals are also allowing 362.0 yards per game.

### **Predictions for Today’s Top NFL Games**

The pick is **New York +1.5 at -107**. The Giants have covered two of three games, are 2-0 at home and have allowed 18.3 points per game. Arizona has also covered twice, but New York owns the stronger defensive profile.

New York is +114 on the moneyline. Wit

### **Potential Upsets to Watch**

h the spread below two points, an outright Giants win is well within reach if their defense limits Arizona’s passing game.

## **NFL Betting Angles for Today**

The NFL odds make the spread the clearest starting point. New York gets 1.5 points at home, while Arizona has dropped two straight.

### **Spread and Moneyline Betting Angles**

Our preferred side is **Giants +1.5 at -107**. New York’s defensive numbers and 2-0 home record support taking the points. The +114 moneyline offers a higher return for bettors who prefer the outright win.

### **Player Prop Betting Angles**

**Cam Skattebo anytime touchdown at -130** is the player prop to consider. Skattebo leads New York with 177 rushing yards, and Arizona allows 127.7 rushing yards per game. He is the most natural touchdown target among the NFL players in this matchup.

## **Final NFL Games Today Outlook**

These NFL teams enter with the same 2-1 ATS record, but New York owns the better defensive profile and a 2-0 home mark. Prime Sportsbook has Arizona -1.5 and the total at 44.5. Our NFL predictions favor **Giants +1.5 at -107**, while Cam Skattebo anytime touchdown at -130 is the preferred player prop. Arizona has the stronger offensive numbers, but New York’s defense gives the Giants a realistic chance to win outright.

## FAQ

### Who Plays Football Tonight in the NFL?

Sunday night brings Detroit at Carolina at 8:20 pm Eastern on NBC. Cardinals-Giants is part of the earlier 1 pm Eastern window on CBS.

### Where Can I Find NFL Odds for Today’s Games?

[**Prime Sportsbook**](https://www.primesportsbook.com/sports/football/nfl/) has Arizona -1.5 at -109 and New York +1.5 at -107. The moneyline is Cardinals -130 and Giants +114, with the total at 44.5.

### What NFL Stats Are Most Important Before Betting?

For Cardinals-Giants, start with how New York defends and how each team runs the ball. The Giants allow 329.0 total yards per game, while Arizona gives up 127.7 rushing yards. Those numbers help explain why New York can remain competitive despite its low-scoring offen

### Why Do NFL Lines Change Before a Game?

The market can react to player availability, weather or changes in betting pressure. Here, Arizona has stayed close to a 1.5-point favorite, while the total has risen from 42.5 to 44.5.

### Which NFL Players Should I Watch in Today’s Games?

Jacoby Brissett, Jeremiyah Love and Trey McBride are central to Arizona’s offense. New York’s key names include Cam Skattebo, Jaxson Dart and Isaiah Likely, while Jevon Holland enters with three interceptions.

Source: https://www.primesportsbook.com/gaming-insider/nfl-games-today-cardinals-vs-giants-odds-predictions/